An Organ-On-Chip (OOC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems, a type of artificial organ. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing. Organ-On-Chip technology not only incorporates multiple cell types but also involves engineering aspects, such as the guided spatial confinement of cells or the incorporation of sensors and microfluidic channels.
The primary focus of Organ-On-Chip technology is the re-creation of three key aspects of human physiology: the multicellular vascular or epithelial interfaces of organs (for example, blood vessel networks, lung and gut), which function as barriers in tissues; the tissue-level organization of parenchymal cells (for example, liver, heart, skeletal muscle and tumours), which are responsible for the key functional properties of an organ; and the systematic interaction of multiple organs (for example, drug absorption, distribution, metabolism and elimination involving the gut, circulation, liver and kidney).
In addition, the Blood-Brain Barrier is definitely more complex than a simple wall, controlling the passage of most solute that enters or leaves the brain. To address how this molecular sieve affects neural activity, some researchers have simulated the interaction between blood vessels and brain tissue on a series of interconnected "organ chips" when connected through this Blood-Brain Barrier (BBB) model. Endothelial cells, pericytes, astrocytes and neurons alter their gene expression. These technologies will achieve even more rapid development and application.
Highlights
The global Human Organs-on-Chips market is projected to reach US$ million by 2029 from an estimated US$ million in 2023, at a CAGR of % during 2024 and 2029.
Global key players of Human Organs-on-Chips include Emulate, TissUse, Hesperos, CN Bio Innovations, Tara Biosystems and Draper Laboratory, etc. Top five players occupy for a share about 46%. North America is the largest market, with a share about 42%, followed by Asia-Pacific and Europe. In terms of product, Liver-on-a-chip is the largest segment, with a share over 28%. In terms of End User, Academic & Research Institutes is the largest market, with a share over 40%.
Report Scope
This report aims to provide a comprehensive presentation of the global market for Human Organs-on-Chips, with both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Human Organs-on-Chips.
The Human Organs-on-Chips market size, estimations, and forecasts are provided in terms of sales volume (K Units) and revenue ($ millions), considering 2022 as the base year, with history and forecast data for the period from 2018 to 2029. This report segments the global Human Organs-on-Chips market comprehensively. Regional market sizes, concerning products by types, by application, and by players, are also provided. The influence of COVID-19 and the Russia-Ukraine War were considered while estimating market sizes.
For a more in-depth understanding of the market, the report provides profiles of the competitive landscape, key competitors, and their respective market ranks. The report also discusses technological trends and new product developments.
The report will help the Human Organs-on-Chips manufacturers, new entrants, and industry chain related companies in this market with information on the revenues, sales volume, and average price for the overall market and the sub-segments across the different segments, by company, product type, application, and regions.
Key Companies & Market Share Insights
In this section, the readers will gain an understanding of the key players competing. This report has studied the key growth strategies, such as innovative trends and developments, intensification of product portfolio, mergers and acquisitions, collaborations, new product innovation, and geographical expansion, undertaken by these participants to maintain their presence. Apart from business strategies, the study includes current developments and key financials. The readers will also get access to the data related to global revenue, price, and sales by manufacturers for the period 2018-2023. This all-inclusive report will certainly serve the clients to stay updated and make effective decisions in their businesses. Some of the prominent players reviewed in the research report include:
    Emulate
    TissUse
    Hesperos
    CN Bio Innovations
    Tara Biosystems
    Draper Laboratory
    Mimetas
    Nortis
    Micronit Microtechnologies B.V.
    Kirkstall
    Cherry Biotech SAS
    Else Kooi Laboratory
Product Type Insights
Global markets are presented by Human Organs-on-Chips type, along with growth forecasts through 2029. Estimates on sales and revenue are based on the price in the supply chain at which the Human Organs-on-Chips are procured by the manufacturers.
This report has studied every segment and provided the market size using historical data. They have also talked about the growth opportunities that the segment may pose in the future. This study bestows sales and revenue data by type, and during the historical period (2018-2023) and forecast period (2024-2029).
Human Organs-on-Chips segment by Type
    Brain-on-a-chip
    Liver-on-a-chip
    Kidney-on-a-chip
    Lung-on-a-chip
    Heart-on-a-chip
    Intestine-on-a-chip
    Vessel-on-a-chip
    Other Organs
Application Insights
This report has provided the market size (sales and revenue data) by application, during the historical period (2018-2023) and forecast period (2024-2029).
This report also outlines the market trends of each segment and consumer behaviors impacting the Human Organs-on-Chips market and what implications these may have on the industry's future. This report can help to understand the relevant market and consumer trends that are driving the Human Organs-on-Chips market.
Human Organs-on-Chips segment by End User
    Pharmaceutical & Biotechnology Companies
    Academic & Research Institutes
    Cosmetics Industry
    Others
Regional Outlook
This section of the report provides key insights regarding various regions and the key players operating in each region. Economic, social, environmental, technological, and political factors have been taken into consideration while assessing the growth of the particular region/country. The readers will also get their hands on the revenue and sales data of each region and country for the period 2018-2029.
The market has been segmented into various major geographies, including North America, Europe, Asia-Pacific, South America, Middle East & Africa. Detailed analysis of major countries such as the USA, Germany, the U.K., Italy, France, China, Japan, South Korea, Southeast Asia, and India will be covered within the regional segment. For market estimates, data are going to be provided for 2021 because of the base year, with estimates for 2023 and forecast revenue for 2029.
    North America
        United States
        Canada
    Europe
        Germany
        France
        U.K.
        Italy
        Russia
    Asia-Pacific
        China
        Japan
        South Korea
        India
        Australia
        China Taiwan
        Indonesia
        Thailand
        Malaysia
    Latin America
        Mexico
        Brazil
        Argentina
    Middle East & Africa
        Turkey
        Saudi Arabia
        UAE
Key Drivers & Barriers
High-impact rendering factors and drivers have been studied in this report to aid the readers to understand the general development. Moreover, the report includes restraints and challenges that may act as stumbling blocks on the way of the players. This will assist the users to be attentive and make informed decisions related to business. Specialists have also laid their focus on the upcoming business prospects.
COVID-19 and Russia-Ukraine War Influence Analysis
The readers in the section will understand how the Human Organs-on-Chips market scenario changed across the globe during the pandemic, post-pandemic and Russia-Ukraine War. The study is done keeping in view the changes in aspects such as demand, consumption, transportation, consumer behavior, supply chain management, export and import, and production. The industry experts have also highlighted the key factors that will help create opportunities for players and stabilize the overall industry in the years to come.
Reasons to Buy This Report
This report will help the readers to understand the competition within the industries and strategies for the competitive environment to enhance the potential profit. The report also focuses on the competitive landscape of the global Human Organs-on-Chips market, and introduces in detail the market share, industry ranking, competitor ecosystem, market performance, new product development, operation situation, expansion, and acquisition. etc. of the main players, which helps the readers to identify the main competitors and deeply understand the competition pattern of the market.
This report will help stakeholders to understand the global industry status and trends of Human Organs-on-Chips and provides them with information on key market drivers, restraints, challenges, and opportunities.
This report will help stakeholders to understand competitors better and gain more insights to strengthen their position in their businesses. The competitive landscape section includes the market share and rank (in volume and value), competitor ecosystem, new product development, expansion, and acquisition.
This report stays updated with novel technology integration, features, and the latest developments in the market
This report helps stakeholders to understand the COVID-19 and Russia-Ukraine War Influence on the Human Organs-on-Chips industry.
This report helps stakeholders to gain insights into which regions to target globally
This report helps stakeholders to gain insights into the end-user perception concerning the adoption of Human Organs-on-Chips.
This report helps stakeholders to identify some of the key players in the market and understand their valuable contribution.
Core Chapters
Chapter 1: Research objectives, research methods, data sources, data cross-validation;
Chapter 2: Introduces the report scope of the report, executive summary of different market segments (by region, product type, application, etc), including the market size of each market segment, future development potential, and so on.  It offers a high-level view of the current state of the market and its likely evolution in the short to mid-term, and long term.
Chapter 3: Detailed analysis of Human Organs-on-Chips manufacturers competitive landscape, price, production and value market share, latest development plan, merger, and acquisition information, etc.
Chapter 4: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product production/output, value, price, gross margin, product introduction, recent development, etc.
Chapter 5:  Production/output, value of Human Organs-on-Chips by region/country. It provides a quantitative analysis of the market size and development potential of each region in the next six years.
Chapter 6:  Consumption of Human Organs-on-Chips in regional level and country level. It provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development,  future development prospects, market space, and production of each country in the world.
Chapter 7: Provides the analysis of various market segments by type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 8: Provides the analysis of various market segments by end user, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 9: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 10: Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market,  the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 11: The main points and conclusions of the report.
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